B6Bliss --

Are you sitting on Bainbridge, sipping hot toddy (or some other alcoholic concoction) looking at a map of the US???

Being from Seattle, but having lived in several cities that you mentioned as possible bus routes, I assure that many of those are NOT feasible at all.

For example, IAH-SAT would be a 4-5 hour bus ride (if the bus obeyed traffic laws). That would simply be unacceptable.

CLE-CMH is a 3 hour bus ride -- again too long!