I agree it is Priceline all the way-
With only one city so far I have refused to use it in- San Juan, Puerto Rico!
In any other larger city you have a choice of areas ( MG- last time I looked MSY had five areas to pick from).
But in SJU you could be stuck anywhere from the Caribe Hilton- Old San Juan, to basically next to a 737 at the airport (what six miles apart).
If location is no problem- go for it-
but if you're looking to spend most of your time in Old San Juan (pre-cruise maybe), or Condado, or Isla Verde- Don't count on being relatively close to what you want.