Originally Posted by
star_world
Vista does support the ability to create "mount points" where a particular folder (and subfolders) can be given a new drive letter but for normal circumstances there really is no benefit at all from this.
Getting completely OT here, but mount points are the inverse of what you are suggesting. The ability to mount a folder as a drive letter has existed since at least MS-DOS v6.22, and likely much longer; I just don't have a DOS syntax guide from older versions around to check. The command used is subst and it works like a charm. It is still included in Vista today.
Mount points allow a drive to be seen as a subfolder of a different drive, rather than as a different letter. So instead of C: and D: for your boot and data drives you could have C: and C:\Data as the two "drives."