When I was at Airborne Express we regularly delivered to hotels. Previously poster is right about placing guest name and arrival date on the package. Hotels that host conferences or are near or next to conventions centers and such get packages for guests on a regular basis and are used to it. The front desk will usually sign or they will direct the delivery guy to the concierge. Also if you are shipping out of the hotel you can arrange the pickup and leave it at the front desk for the delivery guy to pick up there.