I tried Apple Mail, and found it worked well. I used O2M ($10 and well worth it) to transfer my windows MSOultlook .pst to .mbox. The only thing missing for me was that when you open a mail message in a separate window, there is no way to navigate to next or previous messages.
I installed Entourage and found it also lacked my favored method of navigation--and it seems to be a much messier interface. so back to Apple mail.
After a few days, I am getting pretty used to using 2 finger scrolling to scroll through the email and 3 finger scrolling to advance to the next mail.
I would still like it if I could navigate from message to message when viewing the mail message in a nice large window.