Hm. I think the definition of 'a very good seat' is flexible, to say the least.
Whilst some pax may not mind sitting at the rear of the cabin, it's worth noting that those in rows 40 - 45 will be amongst the last off the plane and may have a longer wait at passport control.
Should I have to choose a seat in Y on an AA 777, I'd consider 21 or 22 B / H rather than sit in row 41. YMMV.