(This list includes stuff in purse, as it interchanges)
Digital camera
Camcorder
Batteries/film for above
Ear plugs (necessity!)
Snacks (don't care for airline food)
Water
Book(s)
Tickets/ID
CC/Cash/Passport
Breath Mints
One change of clothes/underwear
Medicine
Notebook for writing log
Reservations and Contact info for B&Bs/Hotels/etc. (if that's gone, the trip's gone!)

and last but not least... lots of patience!