A former colleague of mine has launched a travel aggregation website.

http://www.prweb.com/releases/2008/08/prweb1176854.htm

http://www.tripchill.com

I've been using it for a few months, helping get most of the bugs out, and have found it to be helpful and easy to use. You send itineraries in for airline, hotel, car rental, iand it puts everything together on one itinerary.

It sends alerts if flights are delayed, and can suggest alternate flights.

It told me my CO flight from LHR was delayed before CO did.

Disclosure: I have no monetary involvement in this, was only an alpha tester.