Hello,
I think strike is always a lottery (and annoying).
LH will for sure switch some aircraft-rotations in case of strike and serve some CL-routes with EN- or mainline-aircraft and cancel some other EN- or mainline-flights instead. It's pretty impossible to know this so far in advance.
For example on Tuesday, there were two flights MUC-ZRH with A319 instead of AVROs; at the first strike, EN came with one rotation to ZRH - while LX was flying with Airbusses all these days.