My AONE - not sure about stopovers!
 

I am not sure if this ANOE route is legal - think I have too many stopovers in continent of origin?

GIB-LGW, LHR-JFK, JFK-MIA, MIA-GUA, GUA-MIA, MIA-LAX, LAX-HKG, HKG-MNL, MNL-HKG, HKG-BKK, BKK-HKG, HKG-JNB, JNB-NBO, NBO-SEZ, SEZ-NBO, NBO-LHR, LHR-DXB, DXB-LHR-GIB.

I think the DXB leg at the end is probably invalid. Could I do a mileage run before my LHR-JFK, and do LHR-DXB-LHR-JFK all in one go without any 24hr stopovers?

Thanks in advance

If each comma separated group indicates a stopover then, yes, you have one too many in Europe. You can eliminate it any way you desire but if you've never been to DXB, I would recommend keeping that stopover as it is worthwhile visiting there.

Using your suggestion about visiting DXB at the beginning of your trip:

GIB-LGW, LHR-DXB, DXB-LHR-JFK...NBO-LON (ground LHR-LGW)-GIB