Cinnarizin (brand name Stugeron in the UK) works wonders for me, with no side effects. It's not sold in the US. I stock up in Asia (or Europe).

The missus uses ginger and Gravol/Dramamine with decent success. When she gets sea/motion sick, her tummy gets all acidic and she gets burpy.

I got seasick on my first cruise. Have made it through 3 more including a 7 day Alaska cruise from Seattle a couple weeks ago with the wrist bands.

Has anyone tried those goofy looking glasses? I just ordered some from Amazon.
I have ginger, wrist bands, Bonine and patches. The more I read about the behind the ear patches, the more inclined I am to save them as a last resort--lots of side effects. The glasses look stupid but I could try them in the room first.

The only time I was prone to seasickness on a cruise was on the Drake Passage. I had brought ginger onboard, but it didn't help me at all. Everyone else on the ship was using scopolamine (the patch), so I joined them and it worked. The only side effect for me was dry mouth.

The bottom line is that you have to find what works for you. Everyone reacts differently.

I don't get motion sickness and enjoy a cruise more when the weather gets rough. My wife however is somewhat prone to seasickness and her favorite remedy is an all inclusive seaside resort.

Update---I did not get sick. I started with taking Bonine the morning of the day of boarding as well as wearing the wrist bands and some ginger from time to time. The first couple days were a little bit choppy but not the kind of motion that would make me nauseous but enough to make it weird to sleep. One the third day I gave up on the wristbands--very uncomfortable and tight. As it turned out, I continued to take Bonine the entire trip just to be on the safe side and all was great. I still am not sure I would do well in open rough waters. I did notice several people with the ear patches but no one with the goofy glasses although I brought them to dinner one night as a joke.
I loved that the ship often had ginger featured ---I had a ginger Cosmopolitan and some ginger dessert and another ginger type cocktail.

Mrs BV gets ill, I enjoy the ships motion. She tried the scop patch, but something about it bothered her. He does suffer from an irregular heartbeat, so maybe the patch exacerbated it. I cannot take motion sickness medication due to glaucoma (read your packaging before taking anything) so I am fortunate I don’t need it. She has tried ginger (ale) with no effect but Bonine has been her friend when the seas hit 4-5 meters and higher. She will stay on board if we have to tender to port in any kind of rough seas. The band was a waste of $10.

One Small Tip
 

I was on a small Hurtigruten ship in Norway in November a few years ago. We had hurricane force winds. It was the wildest I have we have ever sailed--everything in the cabin went flying, the mini bar door open and everything scattered. At dinner people were falling out of their seats.

A crew member told me to train my eyes on the horizon for several minutes and stay focused. It worked great.

This is always the best thing if you're able. I've had to do that when on small tour boats in rough seas. While most people won't eat when they're getting quessy, I've found that eating something really helps me.

What's your focus at night?
I agree, something bland in my stomach like bread.

Sleep.

The motion usually rocks me to sleep quickly. I’ve not yet encountered anything bad enough to throw me from the bed, but I have been flung into the corridor walls. Selective application of the drinks package helps me as well.

or "Seabands" brand works for us

I would have to take a lot of cruises to justify spending $180 on a wristband.