cockpitvisit

Reportedly, Covid-19 vaccines in development exceed the natural immunity.

And why should this not be possible? You can increase the dose of the vaccine to produce a stronger immune response (cannot do with with the actual virus, as it would kill the patient).

MaxVO

I meant the immune response being specifically targeted to the currently attacking threat, rather than its facsimile. But hey, if any of the promising claims pan out, I won't care how they accomplished them.

EuropeanPete

I’d certainly look to get a vaccine as soon as possible. If there are multiple candidates I might wait for one which seems more reliable, but not for that long.

I’d not do anything below hand to steal from immuno-compromised people or essential workers, but I’ll be very happy to spend some money on travel and if necessary a private vaccine at the right time.

RedChili

There was a Chinese report not so long ago claiming that people that had a mild case of covid-19 were only immune for 8 weeks. If that is true, it's likely that a successful vaccine will only give immunity for 2-4 weeks.

You can produce a longer immunity by increasing the dose, but that would mean that you're in danger of getting a serious case of the sickness itself.

Also, when taking into consideration how much money is involved, it's likely that several big pharm companies will cut corners to get to market as quickly as possible and make some big bucks, so you'd have to expect some serious side effects. It normally takes about five years before you know if a vaccine is safe and effective. I'd say that taking any covid-19 vaccine before 2025 is risky business. The cure could easily be worse than the disease.

Dublin_rfk

I trust my health and will live with my positive antibody test and certificate.

FlyingSloth

Why not just catch the virus, and that will provide immunity and antibodies for a few months. Even a vaccine will likely only be effective for a few months at most, according to what the scientists are saying now.

Collierkr

The OP doesn’t understand how this vaccine distribution will work. There is no chasing it. Countries are plunking down a lot of money to reserve doses so hope you live in one of those countries if you want it early. Second, there will be a pecking order with those over age of 50 first up. And in the US, you better have insurance, be destitute or be prepared to pay.

my guess is we will not see routine availability until Q1 2021.

cockpitvisit

I couldn't find the article I was referring to when I wrote the original reply to you, but here it is:

First data for Moderna Covid-19 vaccine show it spurs an immune response (statnews.com)
To me, it reads like a stronger immunity is to be expected after the vaccine than after an actual illness.

MaxVO

No, a mass of antibodies alone will not stop an infection -- they must match a specific antigen. Covid (like seasonal flu) constantly mutates, which makes the match difficult. The proof will come from exposed people not getting sick, not from a bunch of in vitro measurements.

cmd320

I'll be giving it a while to see what happens to other people first. The potential side effects of a widely untested vaccine are more concerning to me than potentially catching COVID, at least for now.

Centurion

You want to race? I suggest you do some research before your rush:Timeline Entry: 4/24/1955

The Cutter Incident

Just a few weeks after the landmark press conference announcing success of the vaccine trials, an Idaho doctor reported a case of paralytic polio in a recently vaccinated girl. Over the next few weeks, similar reports trickled in to local health authorities. All involved a disturbing detail: paralysis began in the vaccinated arm, rather than in the legs as was more common.

It soon emerged that most of the cases of paralytic polio occurred in children inoculated with vaccine produced by Cutter Laboratories in California

bensyd

Everything I have read to this point says that this coronavirus does not mutate at all like the flu which makes a vaccine easier to roll out. The exact reason, iirc, was that although this is an RNA virus in one of its building blocks it has what's best described as a checksum that slows its mutation.

cockpitvisit

That's a perfect example of why we shouldn't be too concerned - that serious flaw was quickly detected and the vaccination program aborted, resulting in only 200 serious injuries or deaths.

For comparison: Covid-19 is killing almost twice as many people in the U.S. per day. Stopping the virus is very urgent, even if we have to take risks with a vaccine.

And that was 65 years ago, vaccine development went a long way since then. AFAIK, vaccines developed in the West do not contain the virus at all.

LifeontheBeach

Russia has released it's vaccine for mass production after clearing clinical trials. Expected to be widely used in early August. Though I don't plan to be in Russia for the first batch, but the vaccine is here.

[Personal comment redacted by moderator] Ever hear of Milliionaire visas given by the UK Government in which rich people invest one Million pounds or so and jump the line with a real genuine settlement visa?

That's a very valid observation. And kind of on my mind as well. Maybe I'll give the Russian batch a miss. Try to get the first Western batch.

largeeyes

Given that it's a coronavirus, and the likelihood is that any vaccine will most likely only be effective for a short time(see immunity, common cold), no, I'm not going to go out of my way to get it.

You're living a dream if you think there will be availability Q1 2021.....