Connecting in PTY to United IAH flight
 

My transfee time is 46m, do you think it is enough?

Another question how good copa is in rebooking flights after delayed connecting flight?

46 minutes is doable, physically, because traversing the terminal is quick, and assuming that an airline booked this on one itinerary and you'll already be checked in for the UA flight. But you'll be one of the last to board. You'll have to clear UA's secondary security at the gate. And you'll need your covid paperwork in order too. I'd also look over the history of your inbound CM flight to be sure.

thanks I have single united (016) ticket and history looks good there are some, out of 30 days only two flights delayed for more than 10m but usually they arrive earlier.

If you booked one ticket copa and United, this time is ok.
Your luggage will be move copa to United . Normally with Copa you arrive early to PTY. in case of lost the flight you have two fly pty to iah per day.

in case of you lost your connection and need stay one night in Panama Hotel, when you coming from South America will need COVID test in PTY before go out airport.