I'm a software consultant and have traveled 75-100% Mon-Fri for over 8 years. A full-time travel job can be very rewarding if (and only if, in my opinion):
(1) Your personal/family situation supports it (unattached, attached but childfree, or attached/childed but with incredibly supportive home situation)
(2) You make it a POINT to explore and exploit the cities/towns to which you travel beyond your hotel and its nearby shopping areas - if you limit your movements to only the immediate locales, you're wasting the diversity opportunities that your traveling provides you
(3) You make SURE you attain status with one or more airlines, hotel, and car rental chains; as you've read here in FT, this is a MUST if you hope to do better than just "survive" during your travels