Generally no, however, there can be one exception to this rule.

On some "smart" lithium-ion/polymer battery packs, their management circuitry will measure how much energy has flowed in or out of the battery. This energy accounting is use to keep track of the battery's state-of-charge (SOC) or, how "full" it is.

If this energy counter gets out of calibration you can often reset it by fully discharging then charging the pack. In some cases, this will improve the runtime of a laptop or cellphone as it's internal circuitry has a better idea as to the real SOC of the battery.

Efrem: 2.53MM?!?! My god...one day I'll have that many miles behind me!