The primary changes are that the ticket must now be ISSUED by the Delta employee, rather than just a certificate handed over to the passenger who tickets it themselves. This is being done primarily to cut down upon the increasing amount of S4 passes being sold to third parties.
Also, there are changes in the works dealing with unaccompanied S4 riders being allowed access to premium international cabins. The proposal is that they may ride in BizElite if and only if accompanied by the employee, not otherwise.