From looking at the TSA lists of prohibited items, I would say "yes." Canes are allowed, and monopods are basically just collapsible canes when it comes down to it.

I've brought tripods quite often, but no one would ever think of them as being usable as a weapon. A monopod might be a "weapon" in the same sense as a golf club, baseball bat, etc. I'm sure there are a few screeners out there who will think of it the same way (one of whom works at IAD).

However, I don't like to check baggage unless absolutely necessary.

Experiences? Opinions?