I suppose one could be deviously creative and fly a one-way ticket from Houston to Indianapolis on 2/27 on NW and accidentally miss your connection.
And then a fit of bad luck, one could fly a one-way ticket from Minneapolis to Atlanta on 2/28 on CO and once again miss that darn connection.
I wouldn't make a habit of it, but it would be a good budgetary decision.
It looks like 3:04 p.m. would be the latest MSP departure on CO for a ATL flight via IAH.