Yeah.. a few years ago (when they still had the service) flew SEA-BOS w/ my rather aged cat in F in the space in front of me (no - we were not putting her in luggage). She was good (very quiet)... seatmate didn't even notice she was there until the attendants came over and made a big fuss over her - very sweet.

BTW - no tranquilizers - vets I've had do not consider it a good idea.

My partner had to drive the car cross country instead - which he has never let me forget

ADM