I recently had an AAgent (
) ticket me using my middle name off my driver's license. As it appeared on my driver's license, I didn't have any trouble with the TSA or the airline, EXCEPT:
My AAdvantage number was kicked off the itinerary for a mismatch, but another agent figured it out and added it back on.
Regularly I fly with tickets issued as "Rob" while my ID says "Robert." Never had an issue with that.