Originally Posted by
allis0ncecelia
They both pant and scream on the 20min ride to the vet - so I am a terrified cat mom here.
If they aren't well-adjusted to travel at all, spare everyone (including your fellow passengers who will have to endure their vocal dissatisfaction with the situation...) more stress than absolutely necessary and take the shortest, most direct routing you can find.
Underseat space on the E175 is comparable to the larger aircraft.
This thread has some more positive opinions. .