TLV is not clean so you will need to go through security in ZRH. Follow signs for connecting passengers. You’ll arrive and depart from E so you just get funneled through a little security checkpoint in that concourse that is used for connections (main security for other departing passengers is at Concourse A).
Extra “security” for US departures means a check of your documents (passport etc.) just in front of the gate area, after you leave the SEN lounge, so leave a bit early. They’ll check that you have your papers in order to enter the US and may ask a few questions. If you are SSSSelected for extra security then you will be asked to go to a little security checkpoint right by the US departure gates to have your bags inspected, be swabbed for explosives, etc. but this only applies to a small number of the passengers.
SEN lounge will have hot food, a salad bar, some kind of dessert. If you’re there around a regular meal time then they’ll be cooking the hot dish live so at least it’s fresh. Food is decent.