For Marriott hotels: the Marriott is the easiest to get to because it's right at the Hauptbahnhof (main train station), which you get to via a 10-minute train ride from the airport. The next easiest is the Renaissance, which requires making a connection to a different train either at the main station or at Oerlikon. It's one train stop away from the main station / town center, which is a 2 minute train ride or 20 minute walk. The Four Points is the farthest from the town center but is right next to a shopping center and some food options, called Sihlcity.
Personally I will generally prefer to stay at the Marriott unless the prices are too high, in which case I go to the Renaissance.