Two points.
First, if you currently have NEXUS, as long you applied before your current membership has expired, you can continue to use your benefits until the renewal is finalized up to 6 months after your expiration date (
source). You may or may not need to be interviewed. If you need an interview, you can wait until after you have received your new passport and have the passport information updated at the interview, otherwise update the passport information in your TTP account.
Secondly, if you were to apply for Global Entry - I am not sure if that option is available on the TTP website while the NEXUS renewal application is pending - your NEXUS card will be deactivated upon final approval of your Global Entry membership (
relevant thread).
ETA: @
mnbp types faster than me.