Connecting pax notwithstanding, CLE under CO/SkyTeam was a reasonable O/D point to EU. But every attempt to make a go of it was inevitable met with indifference and ingratitude. We who are not suffer.
Why would you think CLE-LON would work on O/D? The only US metros similar in size to Cleveland that have London flights are either big leisure destinations (MSY, LAS, the aforementioned CHS on a seasonal basis) or big tech hubs (AUS, RDU).