I'm usually pretty adventurous when eating outside of the US. I was in India for 10 days traveling with locals, so eating at some pretty cheap hole in the wall style places that most westerners wouldn't have gone to. No problems what so ever until the last day. Had the runs for about 36 hours after grabbing some food from a street vendor in Delhi. Nothing serious, but probably only the 2nd time food has ever adversely affected me while traveling.