Maybe check out the hotels around the Bugis area?
Bugis isnt too far from Arab st/Little India and I feel that the Bugis area is more interesting and has more sights nearby.
Can walk to Arab st, Little India, Colonial district, Fort canning park, Marina Bay
Lots of eateries around too.
Around One Farrer surrounding area, there are just mostly government flats(apartment buildings), shophouses in Little India nearby, mostly indian restaurants and shops.
Nothing much other than that, quite residential.