Travel insurance: Yay or Nay?

We travel luxe most of the time and historically I have not availed myself of travel insurance and only once have suffered therefore. But I recently booked a VERY expensive trip and chose to insure it for a hefty premium.

And I feel like a chump. But I have good reasons to seek protection with so many big bucks at risk: my husband is in mid-stage dementia and I have lupus, albeit generally well behaved. So, I swallowed the bait this time. Would you?