Welcome to winter travel in the Northeast,
SFO777
We go to Israel usually one time per year, and LH has always been the carrier of choice ex-Boston due the wide body service on the TLV leg. Second choice was LX. But, as you note with the utilization of A321s for FRA and ZRH, which is not a negligible distance especially for the price, we've gone back to the drawing board with UA looking the most promising with their 773 ex-EWR. We've also done BA, who have 777s as well, but the connection timing isn't great and you have to connect in LHR.
Thanks for a great report! Enjoy Israel.