I think I'm almost immune to advertising (OK, experts will say otherwise) but as long as they are not intrusive, visually or physically, I can ignore them happily.
What REALLY gets my goat is when free-standing placards obstruct my movement, or when they're stuffed down my face on BA's IFE.
Oh, and the adverts on Flyertalk, which are a massive PITA, especially on iPad with a slow connection.