Lol this thread is hilarious. I'm honestly not sure if some people are being serious or are seriously that crazy..
Very simple. Are you going straight to work when you land? If so, stay up front and arrive rested and buy your wife a nice spa day to relax from being left in the back. If you have the day off after arriving I would give my wife the seat up front and reap the rewards later that night; if your back allows it
On a separate note, how do meals work if you switch seats? If you have a D1 meal and then switch, would they then offer the wife a meal as well?