I wouldn't say it's likely, but probably best to be prepared and cautious. 5* hotels in India are very careful about food handling. I've been to India a few times, staying in a combination of 4 and 5 star hotels, homestays and safari lodges and have not got ill yet, and I don't have a particularly strong stomach. People generally recommend eating yoghurt (which they call curd) with meals, and avoiding salad /fruit that you eat the peel of (though I have eaten salad and fruit without problem in 5* hotels) and not eating street food. Vary eating Indian and western food, as eating spicy food constantly when you're not used to it is likely to upset your stomach irrespective of hygiene issues. Also, if you are taking anti-malarial drugs, these can upset your stomach, so do follow the instructions on how to take them.