Welcome.
MSP is my home base as well. With Comfort Plus, but no Gold Medallion or above status, you will NOT be able to use the Sky Priority security area. You WILL be able to board with zone SKY (right after Premium/First Class).
However, if you have TSA Precheck, you may use the Precheck line, which is right next to the Sky Priority security area.
If you are a business traveler, I would highly recommend looking at TSA Precheck, or for a few dollars more, Global Entry, as a way to get the Precheck status. It really does help speed through MSP security faster--most of the time.