Yes it is fine. Easy. Send the companies some emails before to be sure you have a reservation, though 1-3 days in advance should be enough. My only usual comment is the night driving on longer distance trips can be a little challenging. For local trips to Uco Valley it is less of a concern.
A few months ago there was a similar question, so I will not repeat all the same thoughts:
http://www.flyertalk.com/forum/argen...car-april.html
Originally Posted by
BostonGuy
I've had great luck with Miguel Sanz and Trout & Wine tours on previous trips, but I want to explore the Uco Valley more deeply.
I'm torn - it's wonderful to be able to sample wines without worrying about driving, but I really like the flexibility of my own car.
Have other Americans rented cars down there? Safe? Easy or difficult?