Originally Posted by
will2288
4 - flying short flight first (so BOS-JFK-BRU is better than BOS-LHR-BRU)
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Interesting that you prefer the short flight first. I prefer the short flight second. If your short flight is late, you could miss your transatlantic which could result in waiting an entire day for the next flight. If you miss your short flight in Europe, there is almost always another which you can take.
Otherwise, your preferences match mine.