1) Be careful of temperature differences -- removing the machine from a cold-ish hold and turning it in the 100F heat of a safari may cause condensation, so let the machine get used to the temperature change.
2) Remove the battery, or tape over the power contacts so make sure it doesn't turn on. A laptop that turns on inflight packed around clothes may create heat damage.
No other technical issues come to mind, and I'll spare you the lecture on never packing a laptop in checked luggage
Have a great trip.