I've stayed at the Residence Inn Las Vegas Hughes Ctr several times and enjoyed it. It is not the typical RI. It is an actual hotel, with something like 11 floors a nice lobby, pool, basketball court, etc...
My reasons for staying there were different then most going to Vegas, so please read on.
1. They have 2 Bedroom Suites available, I was traveling with several non-family members.
2. I was attending a car race (with my race car on a trailer) that needed a large, fairly secure parking lot. This hotel has PLENTY of free parking for trailers.
3. I wanted free breakfast. All RI's have it.
A good choice for a hotel NOT near the strip, but near some good casinos and restaurants...