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Old Aug 13, 2016, 8:12 am
  #1  
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Unhappy Kinerase Gone :(

Years ago, and at the recommendation of many people in this forum, I started using Kinerase. It wasn't cheap, but it did appear to work.

It appears that Valeant Pharma has sold/spun off that division to Obagi. I wrote to them and they indicated that the products were gone and suggested their product called Gentle Rejuvination which contains Kinetin and Zeatin. They did say the products were not exactly the same. It also appears they're not wildly available and can be purchased through dermatologists, though I have seen the products sold at a few online retailers.

So, ladies, what creams are you using? I'm now a 50-something and have been using Kinerase for about 10 years. I still have 1 tube in the fridge, but am out of the eye cream
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Old Aug 14, 2016, 8:22 pm
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I'm missing Kinerase too! I have been using La Mer products and stock up on them in Germany. A few things sold there I can't find in the US and prices are a bit better.

Kinerase's active ingredient in the eye cream I think we both used was furfuryladenine. I haven't looked much to see if any other products might contain it. Retin A comes closest to it, but is more drying, stronger and by script. I have used Retin A and find it pretty harsh on my skin, but it is proven to be effective in studies.
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Old Aug 15, 2016, 6:23 am
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I think furfurydalenine may be kinetin. I will look some more.

I hesitate to use Retin A, even in the OTC form, because it's not as gentle. From what I've seen on the Obagi website and their email, it appears the Gentle Rejuvination line is also gentle for sensitive skin.

I can't bring myself to buy La Mer products... they're price is beyond what my stomach can tolerate
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Old Aug 15, 2016, 8:20 am
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Explains the chemicals v trade names.
http://www.smartskincare.com/treatme...e_kinetin.html

Older story about effectiveness of Retin A: http://mobile.nytimes.com/2006/11/30...skin.html?_r=0
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Old Aug 26, 2016, 11:25 am
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I finally got around to looking who might be selling Obagi products and there are a few websites.

I ordered the Ultra Rich Gentle Rejuvination eye cream from Amazon today. The reviews were mostly positive, and it contains kinetin and zeatin, so I'm hoping it's pretty much the same. It cost $55, and I did see prices around $80, which is what Kinerase sold for. The Obagi website does not contain prices - they only sell the MDs.

Will keep you posted.
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Old Jan 29, 2017, 9:48 am
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UPDATE....

I finally started using the eye cream I ordered back in August. I hadn't run out of Kinerase yet.

I'm liking it more than the Kinerase eye cream. Too bad Obagi isn't that widely available. It seems to be something that is sold in doctor's offices only - and of course, on Amazon.

I don't need face cream yet. I still have a tube in the refrigerator.
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Old Jan 30, 2017, 9:47 am
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Last year my derm was selling Obagi products (I have a couple of the prescription items) but this year they aren't - I think she said they changed the formulation and the MD doesn't like it? I'm about to go in to replace my tretinoinin so I'll see what they have now....

I need a new night cream so I'm shopping around
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Old Jan 30, 2017, 9:50 am
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Perhaps they changed the formulation of the particular line they're selling. Obagi has several, and I really only looked at the Kinerase equivalent (gentle rejuvenation)

But I looked at the pricing again on Amazon, and the eye cream is now up to $102 a tube. That may be more than I'm willing to spend.
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Old Oct 28, 2017, 6:27 pm
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OBAGI

Thank you for the tip about Obagi. I can't wait to try it. I loved kinerase and it helped my eye lid tremendously. It was the only cream endorsed by my dermatologist and eye surgeon. my eye lid had been cut off in an auto accident and is pieced together from left over skin on my head. I found Obagi for 55$ at Walmart. Much better than the 102 price tag from Amazon.
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Old Dec 21, 2021, 11:35 pm
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Thank You!

Thanks for posting this ladies!
After Kinerase was discontinued I looked and looked for a cream/serum with Kinetin and Zeatin. I couldn’t find anything so I tried so many other products…..SO MANY! Recently I started looking again and ran across this thread. I ordered the Gentle Rejuvenation Ultra-Rich Eye Hydrating Cream and the Kinetin Rejuvenating Serum Obagi Clinical. Couldn’t tell what year this was posted either. It only showed the month and day (no year, it’s Dec 2021 today). I hoped it wasn’t years ago and that Obagi would still be available. I found these on Amazon and started using them two weeks ago. Both are just as effective for me as Kinerase was!! I lost a few years in there but at 53 I’m so glad to have this as an option again! I am very grateful. So thanks again

Edited….
OMG….was this 2015-2017? Wow, I had a couple of bottles to use after these were discontinued but was it really 6 years ago? Oh my!
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Last edited by TheDeev; Dec 21, 2021 at 11:48 pm
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Old Jan 2, 2022, 2:57 pm
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Originally Posted by TheDeev
Thanks for posting this ladies!
After Kinerase was discontinued I looked and looked for a cream/serum with Kinetin and Zeatin. I couldn’t find anything so I tried so many other products…..SO MANY! Recently I started looking again and ran across this thread. I ordered the Gentle Rejuvenation Ultra-Rich Eye Hydrating Cream and the Kinetin Rejuvenating Serum Obagi Clinical. Couldn’t tell what year this was posted either. It only showed the month and day (no year, it’s Dec 2021 today). I hoped it wasn’t years ago and that Obagi would still be available. I found these on Amazon and started using them two weeks ago. Both are just as effective for me as Kinerase was!! I lost a few years in there but at 53 I’m so glad to have this as an option again! I am very grateful. So thanks again

Edited….
OMG….was this 2015-2017? Wow, I had a couple of bottles to use after these were discontinued but was it really 6 years ago? Oh my!
Happy to see the powers of search engines & online forums score a win! I'm horrible about using product consistently so I label my skincare purchases with Purchase Date & Open Date so I don't inadvertently give myself a rash or worse.

ETA: There's an app which reads beauty product barcodes to provide expiry info http://beautykeeperapp.com/
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Last edited by freecia; Jan 2, 2022 at 3:05 pm
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Old May 10, 2022, 7:05 pm
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Originally Posted by l etoile
I'm missing Kinerase too! I have been using La Mer products and stock up on them in Germany. A few things sold there I can't find in the US and prices are a bit better.

Kinerase's active ingredient in the eye cream I think we both used was furfuryladenine. I haven't looked much to see if any other products might contain it. Retin A comes closest to it, but is more drying, stronger and by script. I have used Retin A and find it pretty harsh on my skin, but it is proven to be effective in studies.
About 6-8 months ago, I dove into La Mer. I wanted to love it, but it didn’t agree with my skin. I did love the cleansing water… that is fabulous.

I fell into skinceuticals phyto calming serum and it’s amazing. Truly amazing, but I have sensitive, reactive skin (I’m in my early 50s). https://www.skinceuticals.com/phyto-...494114003.html 10/10 recommend
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Old Aug 8, 2022, 3:34 am
  #13  
 
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Crazy that this thread is here. After Kinerase started disappearing I stocked up on my favorite Kinerase Gentle Daily Cleanser. This was recommended to me when I started using Retin-A for melasma over 15 years ago and it is has served me well. I think I have bought all of them that have popped up on eBay over the years. I'm currently nearing the end of my last tube and I don't know what to try next.
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Old Jun 8, 2023, 9:48 am
  #14  
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Has anyone else tried Epionce?

I got it from my 30-year-old son, of all people. One of his dermatology medical colleagues is a recommended that. My son bought it for me and I love it. He’s bought me a few other face creams for various purposes, but I like that the best.
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