I am trying to work out the schedule for a business trip over a week's time. I will be arriving in Madrid on a Tuesday afternoon, and departing also from Madrid the following Monday. I need to be in Murcia, Bilbao, and then either Seville or Salamanca during that time period, for meetings scheduled on business days. What would be the most efficient way to move between cities? Rental Car? Train? Flights? All suggestions would be appreciated.