Hertz - Toyota Sienna

Can a Toyota Sienna fit 7 passengers and 7 luggages? What do they mean when they say medium sized luggage anyway?

A Sienna will seat at least 7, though there are 8 passenger models as well. Not sure what you mean with luggage, but I used to drive an 8-pass one as a shuttle van and we could easily fit 4-5 large suitcases and 8 people in it.