Only when I can't get the whacky tray table to go back where it belongs and I have to climb over it. There's just something about that thing that seems to enjoying messing with me.
LOL that table mechanism is a nightmare.
Positive for odd numbers- you're farther away from the aisle. Psychologically I feel like I can sleep better.
Negative is that if you're right-handed (which I am) it's not ideal (thought not uncomfortable) to do work if you're on the K side of the aircraft.