If there is a 30/60/90 type sale this year, consider trying to link together a bunch of the 30s into a segment run. Under RR1, it was almost never worth it unless you had expiring credits or were trying to renew A-List (saving all the EB $10 surcharges). But now with A+, anybody who would get 35-45 segments in a year through normal travel has to seriously consider it.
Do some research about the flight schedules in your region and understand which flights link well (without the same flight number) before there's a fare sale. My goal is to have a couple of 3-segment one-ways planned out to and from locations I'd like to visit in April/May and especially Oct/Nov, as based on my spending patterns I've figured out that an extra $250 invested into A+ would be a great ROI.